Isolated Tracheobronchial Amyloidosis

The tracheobronchial amyloidosis is a rarely localized form. It may manifest as a cancer. Only histological results allow diagnosis confirmation. A 68-year-old man was admitted for exploration of a low abundance hemoptysis. The chest radiograph was normal. CT scan objectified thickening of the walls of the trachea and bronchi which are the seat of calcifications. Bronchoscopy found a burgeoning infiltrative lesion training the right side face of the trachea and the anterior edge of the hull. Histological results confirmed tracheobronchial amyloidosis. Typing of this amyloidosis concluded to AL form. The study of amyloid extension lesion was negative. Immunoelectrophoresis of proteins in the blood and urine was normal. The patient was sent to receive external beam radiation to prepare for endoscopic surgical removal. Post-operative suites were marked by a complete resolution of clinical signs particularly hemoptysis with a follow-up of two years.